Like the title suggests, is there any reason to keep 0 pointers? The resources take months if not years to amount to being even worth raiding, why do you keep them?
Note this is for the 0 points only, not ALL inactive.

Or perhaps these NON generated inactives could be made more profitable.

I fully agree with this. And if they are an integral part for new players, then have them last something like 3 to 12 months then fall off.

That would be a good reason, if they have never been hit (we are talking accounts I've seen well over a year now, and I only made this post after having hit them a full year later, where they are just getting full.)